Ergot poisoning could be responsible for many of the recorded miracles.
It could be responsible for many of the recorded visions of God. It also could be responsible for some of the major ancient wars. This seriously could have effected a lot of our written history. It is actually a pretty intertesting subject.

Basically, the CIA did mind control experiments and used various drugs, like truth serum, amphetamines, and LSD and a number of other hallucinogens and psychadelics (even marijuana). It's strange, strange stuff. They also looked into torture techniques used by governments around the world. Eventually, they adopted a couple techniques used by Russia - self-inflicted pain and sensory deprivation. Guess where these techniques have been used recently.

Anyway, here's the wikipedia link:
http://en.wikipedia.org/wiki/MKULTRA

Also check out CoIntelPro if you don't already know what it is:
http://en.wikipedia.org/wiki/Cointelpro

It's been theorized that CoIntelPro may have even been involved with the Assassination of Martin Luther King Jr., but that's something for the Conspiracy Theories forum. Though, it is certain that they've been involved in a number of assassinations- black panther party memebers, the attempted assassination of environmental activists Judi Bari & Daryl Cherney, etc.

COINTELPRO is an acronym for a series of FBI counterintelligence programs designed to neutralize political dissidents. Although covert operations have been employed throughout FBI history, the formal COINTELPRO's of 1956-1971 were broadly targeted against radical political organizations. In the early 1950s, the Communist Party was illegal in the United States. The Senate and House of Representatives each set up investigating committees to prosecute communists and publicly expose them. (The House Committee on Un-American Activities and the Senate Internal Security Subcommittee, led by Senator Joseph McCarthy). When a series of Supreme Court rulings in 1956 and 1957 challenged these committees and questioned the constitutionality of Smith Act prosecutions and Subversive Activities Control Board hearings, the FBI's response was COINTELPRO, a program designed to "neutralize" those who could no longer be prosecuted. Over the years, similar programs were created to neutralize civil rights, anti-war, and many other groups, many of which were said to be "communist front organizations." As J. Edgar Hoover, longtime Director of the FBI, put it
http://www.icdc.com/~paulwolf/cointelpro/cointel.htm